李茹 教授，博士,博士生导师
E-mail:liruonly@163.com
个人简介：
2010年在中国科学院武汉病毒研究所获得博士学位；2010年至今在广西大学开云在线注册,开云(中国)生物技术系工作。目前主要从事甘蔗抗病以及甘蔗黑穗病菌致病机制的研究。主持国家自然科学基金3项、广西自然科学基金2项；参与国家973计划课题1项，发表论文20余篇。
教学和科研成果：
主讲《分子生物学》、《生物化学》等本科课程；主持国家自然科学基金3项、广西自然科学基金2项；参与国家973计划课题1项，发表论文20余篇。
主持承担的主要科研项目：
1.国家自然科学基金，板栗疫病菌基因组DNA甲基化与毒力调节的关系，50万元，2013.01-2016.12，主持；
2.国家自然科学基金，MicroRNA对板栗疫病菌毒力的调控机制研究，2016.01-2019.12，40万元，主持；
3.国家自然科学基金，乙酰化修饰对板栗疫病菌毒力的调控机制研究，2018.01-2021.12，40万元，主持；
4.广西自然科学基金，MicroRNA对甘蔗黑穗病菌有性配合的调控机制研究，2018.07-2021.07，12万元，主持；
5.973计划项目，真菌通讯系统的揭示和调控机理，2015.01-2019.12，300万元，主要参与；
6.广西甘蔗生物学重点实验室自主研究课题，甘蔗抗黑穗病和梢腐病性状形成的分子基础及其调控机制，2019.07-2021.12，200万元，主要参与。
研究方向：
1.甘蔗抗黑穗病的分子基础及调控机制；
2.植物病原真菌（甘蔗黑穗病、板栗疫病菌）致病机制及与宿主互作机制。
指导的学生获奖：
代表性论文：
(1)李茹;白山;何媛媛;陈琦;王金子;陈保善*; Cpvma1, a vacuolar H+-ATPase catalytic subunit of Cryphonectria parasitica, is essential for virulence and hypovirus RNA accumulation,Phytopathology, 2019, 109(8): 1417-1424.
(2)李茹;周思思;李永兵;沈笑瑞;王志强;陈保善*; Comparative Methylome Analysis Reveals Perturbation of Host Epigenome in Chestnut Blight Fungus by a Hypovirus.,Front Microbiol, 2018, 9: 1026-1026.
(3)李茹;谷晶;陈媛媛;肖传乐;王利伟;张治平;毕利军;危宏平;王绪德;邓教宇*;张先恩*; CobB regulates Escherichia coli chemotaxis by deacetylating the response regulator CheY,Molecular Microbiology, 2010, 76(5): 1162-1174.
(4)李茹;陈鹏;谷晶;邓教宇*; Acetylation reduces the ability of CheY to undergo autophosphorylation,FEMS Microbiol Lett,2013, 347: 70-76.
(5)廖素环#;李茹#;施李鸣;王金子;商巾杰;朱平川;陈保善*; Functional analysis of an S-adenosylhomocysteine hydrolase homolog of chestnut blight fungus,FEMS Microbiol Lett, 2012, 336: 64-72.
(6)施李鸣;李茹;廖素环;白凌云;陆群凤;陈保善*; Prb1, a subtilisin-like protease, is required for virulence and phenotypical traits in the chestnut blight fungus,FEMS Microbiol Lett, 2014, 359: 26-33.
(7)Chen, Qi; Li, Yongbing; Wang, Jinzi; Li, Ru;Chen, Baoshan*; cpubi4 Is Essential for Development and Virulence in Chestnut Blight Fungus,Frontiers in Microbiology, 2018, 9: 0-1286.
(8)陈鹏*;李茹;周瑞阳; Comparative phosphoproteomic analysis reveals differentially phosphorylated proteins regulate anther and pollen development in kenaf cytoplasmic male sterility line,Amino Acids, 2018, 50(7): 841-862.
(9)Chen, Peng*; Wei, Fan; Li, Ru; Li, Zeng Qiang; Kashif, Muhammad H; Zhou, Rui Yang; Comparative acetylomic analysis reveals differentially acetylated proteins regulating anther and pollen development in kenaf cytoplasmic male sterility line ,Physiologia Plantarum, 2019, 166(4): 960-978.
(10)Chen, Peng*; Shi, Qiqi; Liang, Zhichen; Lu, Hai; Li, Ru; Comparative profile analysis reveals differentially expressed microRNAs regulate anther and pollen development in kenaf cytoplasmic male sterility line ,Genome, 2019, 62(7): 455-466.
(11)李茹;谷晶;陈鹏;张治平;邓教宇*;张先恩*; Purification and characterization of the acetyl-CoA synthetase fromMycobacterium tuberculosis,Acta Biochim Biophys Sin, 2011, 43(11): 891-899.
(12)李茹;李洋;李林生;廖素环;白凌云;陈保善*;板栗疫病菌ntl基因的功能研究,基因组学与应用生物学, 2013, 32(4): 420-427.
(13)李林生;周思思;姚颜萍;廖素环;陈保善;李茹*;板栗疫病菌cpomt基因的功能,基因组学与应用生物学, 2017, 36(1): 1-6.
(14)桂磊;李茹;白凌云;何熙谱;林海燕;陈保善*;低毒病毒-板栗疫病菌系统作为抗正链RNA病毒化合物筛选模型的研究,基因组学与应用生物学, 2014, 33(5): 975-981.
(15)阎维巍;李茹;陈保善;高效甘蔗黑穗病菌原生质体的制备,基因组学与应用生物学, 2016, (07): 1750-1755.
(16)陈鹏;廖剑;黄志鹏;李茹;赵艳红;冉珊敏;周瑞阳*; Comparative Proteomics Study on Anther Mitochondria between Cytoplasmic Male Sterility Line and its Maintainerin Kenaf (Hibiscus cannabinus L.),Crop Science, 2014, 54: 1103-1114.
(17)Gu, Jing; Deng, Jiao-Yu; Li, Ru; Wei, Hongping; Zhang, Zhiping; Zhou, Yafeng; Zhang, Ying;Zhang, Xian-En; Cloning and characterization of NAD-dependent protein deacetylase (Rv1151c) from Mycobacterium tuberculosis,BIOCHEMISTRY-MOSCOW,2009, 74(7): 743-748.
(18)陈鹏;冉珊敏;李茹;黄志鹏; Qian Jing Hua; Yu Ming Li;周瑞阳*; Transcriptome de novo assembly and differentially expressed genes related to cytoplasmic male sterilityin kenaf (Hibiscus cannabinus L.),Molecular Breeding, 2014, 34: 1879-1891.
(19)李茹;陈鹏*;细菌趋化性信号传导及调节机制研究进展,生物技术通报, 2011, 27(11): 109-113.
(20)张姗姗;张沛然;兰仙软;李茹;黄有总;陈保善*;中蔗系列甘蔗品种的黑穗病抗性鉴定,中国糖料, 2019, 41(4): 37-40.
